There’s something so comforting about a warm, bubbling casserole coming out of the oven. For me, chicken and spinach casserole is more than just a meal—it’s like wrapping up in a cozy blanket on a chilly evening. This dish is a hearty, creamy classic, full of flavors that remind me of family dinners and potlucks with friends. It’s the perfect blend of savory chicken, tender spinach, and gooey cheese, all tied together with a rich, creamy sauce. Whether you’re looking for a weeknight dinner to feed your family or a dish that impresses guests, this recipe has it all.

It’s also incredibly versatile, making it a favorite in households everywhere. Pair it with a side of crusty bread or a fresh salad, and you’ve got yourself a well-rounded, satisfying meal. Let’s dive into what makes this dish a must-try.

Why You’ll Love This Recipe

1. One-Pan Wonder: This casserole is the definition of easy. Toss everything into a baking dish, pop it in the oven, and let it work its magic. Minimal dishes, minimal stress!
2. Nutritious and Delicious: With spinach as a star ingredient, this dish is packed with vitamins and nutrients while still being utterly indulgent.
3. Family-Friendly: The creamy sauce and cheesy topping make it a hit with kids and adults alike. Even picky eaters love it!
4. Great for Meal Prep: Make it ahead of time, and simply reheat when you’re ready to serve. It also freezes well, making it a lifesaver on busy days.

Ingredients You’ll Need

• 2 cups cooked chicken, shredded or cubed
• 3 cups fresh spinach, chopped
• 1 cup sour cream
• 1 cup cream cheese, softened
• 1 cup shredded cheddar cheese
• 1 cup shredded mozzarella cheese
• 1/2 cup mayonnaise
• 1/4 cup grated Parmesan cheese
• 1 teaspoon garlic powder
• 1 teaspoon onion powder
• 1/2 teaspoon paprika
• 1/2 teaspoon salt
• 1/2 teaspoon black pepper
• 1/4 cup bread crumbs (optional, for a crispy topping)

How to Make Chicken and Spinach Casserole

Step-by-Step Instructions

1. Preheat and Prepare
   Start by preheating your oven to 375°F (190°C). While the oven heats up, grease a 9×13-inch baking dish with cooking spray or a light layer of butter. This ensures that your casserole will come out cleanly and makes cleanup a breeze.
2. Combine the Creamy Base
   In a large mixing bowl, combine the softened cream cheese, sour cream, mayonnaise, and Parmesan cheese. Add in the garlic powder, onion powder, paprika, salt, and black pepper. Stir until smooth and well blended. This creamy base is the heart of the dish—it’s where all the rich, comforting flavors come from.
3. Layer the Ingredients
   Spread the shredded chicken evenly across the bottom of your prepared baking dish. Next, layer the chopped spinach on top of the chicken. Don’t worry if the spinach seems like a lot—it will cook down in the oven.
4. Add the Sauce
   Pour the creamy mixture over the chicken and spinach, using a spatula to spread it evenly. Make sure every corner is covered, so every bite is packed with flavor.
5. Top with Cheese and Breadcrumbs
   Sprinkle the shredded cheddar and mozzarella cheeses evenly over the casserole. For an optional crispy topping, sprinkle a thin layer of breadcrumbs over the cheese.
6. Bake to Perfection
   Place the casserole in the oven and bake for 25-30 minutes, or until the top is golden and bubbly. You’ll know it’s ready when your kitchen is filled with the irresistible aroma of melted cheese and spices.
7. Cool and Serve
   Let the casserole cool for 5-10 minutes before serving. This allows the layers to set, making it easier to scoop out and enjoy.

Helpful Tips

• Make it Lighter: Substitute Greek yogurt for the sour cream or mayonnaise to reduce calories without sacrificing creaminess.
• Protein Options: While chicken is a classic choice, you can use turkey or even cooked tofu for a vegetarian twist.
• Add Veggies: Feel free to mix in other vegetables like mushrooms, bell peppers, or zucchini for added nutrition.
• Fresh vs. Frozen Spinach: Fresh spinach is recommended, but if you only have frozen, be sure to thaw and drain it well to avoid excess water in your casserole.
• Crispy Topping: For an extra-crispy top layer, drizzle a small amount of olive oil over the breadcrumbs before baking.

Recipe Details

• Prep Time: 10 minutes
• Cook Time: 30 minutes
• Total Time: 40 minutes
• Yield: Serves 6
• Category: Main Dish
• Method: Baking
• Cuisine: American
• Diet: Can be made gluten-free if you skip the breadcrumbs or use gluten-free alternatives.

Notes

• If you’re making this ahead of time, assemble the casserole but don’t bake it. Cover it tightly with foil and refrigerate for up to 24 hours. When ready to bake, remove it from the fridge, let it sit at room temperature for 15 minutes, and bake as directed.
• Leftovers can be stored in an airtight container in the refrigerator for up to 3 days. Reheat in the oven or microwave until warmed through.

Nutritional Information (Per Serving)

• Calories: 380
• Protein: 22g
• Carbohydrates: 6g
• Fat: 29g
• Fiber: 1g

Frequently Asked Questions

Can I use rotisserie chicken?
Absolutely! Rotisserie chicken is a time-saving option that works perfectly in this recipe.

Can I freeze this casserole?
Yes, you can freeze the assembled, unbaked casserole for up to 3 months. Wrap it tightly in plastic wrap and aluminum foil before freezing. When ready to cook, thaw it overnight in the fridge and bake as directed.

What can I serve with this dish?
A fresh green salad or roasted vegetables are excellent side dishes. You can also serve it with rice, quinoa, or pasta for a heartier meal.

Related Recipes

If you loved this chicken and spinach casserole, be sure to check out these other comforting casseroles:

• Cheesy Penne with Garlic Butter Ground Beef – Creamy, Savory, and So Satisfying!
• Cheesy Chicken Spinach Bake
• Chicken Alfredo Casserole

Conclusion

Chicken and spinach casserole is the ultimate comfort food that brings people together. Whether you’re serving it for a cozy family dinner or taking it to a potluck, it’s a guaranteed crowd-pleaser. The creamy layers, cheesy topping, and tender chicken make every bite feel like a warm hug. Give this recipe a try, and let it become a staple in your home, just like it has in mine!Enjoy!

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