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There’s nothing quite like a dish that feels indulgent yet manages to come together quickly, making it perfect for both busy weeknights and leisurely weekends. Southwest Chicken Alfredo is a shining example of comfort food that marries creamy richness with bold, zesty flavors. It’s a crowd-pleaser that warms the heart and satisfies the palate. This recipe is inspired by the bold flavors of the Southwest and the timeless appeal of Alfredo pasta, making it a true fusion masterpiece that’s hard to resist.

Picture this: tender, juicy strips of chicken, seasoned with a medley of chili powder, cumin, and smoky paprika, pan-seared to perfection for that golden, caramelized crust. Add to that a creamy Alfredo sauce with just the right kick of spice and tangy diced tomatoes for a burst of freshness. It’s all tossed with perfectly cooked penne pasta and topped with melted cheddar cheese, creating a velvety, cheesy finish that ties everything together. This dish not only delivers on flavor but also brings a sense of warmth and togetherness to the dinner table.

For many, this dish may evoke memories of family meals where lively conversation fills the room, and the tantalizing aroma of spices and cheese wafts from the kitchen. It’s the kind of meal that brings people back for seconds and leaves everyone asking for the recipe. Whether you’re looking for a new family favorite, a dish to impress guests, or just a comforting meal after a long day, Southwest Chicken Alfredo fits the bill perfectly.

Why You’ll Love This Recipe:

  • A Perfect Blend of Flavors: This dish strikes a beautiful balance between creamy, cheesy Alfredo and bold, spicy Southwest flair.
  • Quick and Easy: Ready in about 30 minutes, this recipe is perfect for busy nights when you still want a satisfying homemade meal.
  • Family-Friendly: With its rich flavors and hearty ingredients, it’s a meal that adults and kids alike will adore.
  • Versatile: You can easily customize this recipe with additional veggies or adjust the spice level to suit your preference.
  • Comfort Food at Its Best: It’s indulgent, warm, and utterly delicious—everything you could want in a comfort food dish.

Ingredients You’ll Need:

  • Chicken Breasts: 1 pound, boneless and skinless, cut into 1-inch strips.
  • Penne Pasta: 8 ounces (about ½ pound).
  • Diced Tomatoes: One 15-ounce can, drained.
  • Heavy Cream: 1 cup.
  • Cheddar Cheese: 1½ cups, shredded.
  • Onion: 1 cup, chopped (yellow, white, or sweet).
  • Garlic Cloves: 4 cloves, minced.
  • Honey: 1 tablespoon.
  • Olive Oil: 1 tablespoon (or avocado or canola oil).
  • Butter: 1 tablespoon (salted or unsalted).
  • Cilantro: 2 tablespoons, chopped (for garnish).
  • Southwest Seasoning Blend:
    • 1½ teaspoons chili powder
    • ½ teaspoon cumin
    • ½ teaspoon oregano
    • 1 teaspoon paprika
    • ¼ teaspoon black pepper
    • ½ teaspoon salt
    • ⅛ teaspoon cayenne pepper

How to Make Southwest Chicken Alfredo:

Step 1: Prepare the Seasoning and Chicken

Begin by making the Southwest seasoning blend. Combine chili powder, cumin, oregano, paprika, black pepper, salt, and cayenne pepper in a small bowl. Stir until evenly mixed. Place the chicken strips in a large bowl, drizzle with honey, and sprinkle half of the seasoning mix over the chicken. Toss to coat the chicken thoroughly and let it sit while you prepare the other ingredients. This step ensures the chicken soaks up all those bold flavors.

Step 2: Cook the Pasta

Bring a large pot of salted water to a boil. Add the penne pasta and cook according to the package instructions until al dente. Drain the pasta and set it aside, reserving about ½ cup of pasta water in case you need it to thin the sauce later.

Step 3: Sear the Chicken

Heat olive oil in a large skillet over medium-high heat. Once the oil is shimmering, add the seasoned chicken strips in a single layer. Cook for 4-5 minutes per side until the chicken is golden brown and cooked through. The spices will create a beautiful crust on the chicken, locking in all the flavor. Remove the chicken from the skillet and set it aside on a plate.

Step 4: Sauté the Vegetables

In the same skillet, add the butter and chopped onions. Sauté over medium heat for 2-3 minutes until the onions become soft and translucent. Add the minced garlic and cook for an additional minute until fragrant. Then, stir in the diced tomatoes, letting the mixture simmer for 2-3 minutes to meld the flavors.

Step 5: Make the Creamy Sauce

Reduce the heat to low and pour in the heavy cream. Stir continuously, allowing the cream to warm through and absorb the flavors from the vegetables and spices left in the pan. Slowly add the shredded cheddar cheese, one handful at a time, stirring until the cheese melts completely into the sauce. If the sauce feels too thick, stir in a little of the reserved pasta water until you reach your desired consistency.

Step 6: Combine Everything

Add the cooked pasta to the skillet, tossing it in the creamy sauce to coat every piece evenly. Gently fold in the cooked chicken, ensuring it’s well distributed throughout the pasta. Let everything simmer together for 2-3 minutes so the flavors can meld.

Step 7: Garnish and Serve

Transfer the pasta to serving plates or a large serving bowl. Sprinkle chopped cilantro over the top for a fresh, vibrant touch. Serve immediately while the dish is warm and the cheese is gooey.

Helpful Tips:

  • Control the Heat: If you prefer a milder dish, skip the cayenne pepper in the seasoning blend. For more spice, you can add an extra pinch.
  • Cheese Options: While cheddar is a fantastic choice, you can substitute or mix in Monterey Jack or pepper jack for a different flavor profile.
  • Prep Ahead: Save time by chopping vegetables and preparing the seasoning blend ahead of time.
  • Pasta Choices: Penne is great, but you can also use fettuccine, rotini, or any sturdy pasta that holds sauce well.

Details:

Prep Time: 10 minutes
Cook Time: 20 minutes
Total Time: 30 minutes
Yield: 4 servings
Category: Main Course
Method: Stovetop
Cuisine: Southwest Fusion
Diet: Kid-friendly

Notes:

Feel free to customize the dish with additional vegetables like bell peppers, zucchini, or corn for extra texture and flavor.

Nutritional Information:

Approximate per serving:

  • Calories: 560
  • Protein: 36g
  • Carbohydrates: 40g
  • Fat: 28g

Frequently Asked Questions:

Can I use a different type of pasta?
Absolutely! Any pasta that holds sauce well, like rotini or bowties, will work beautifully.

How can I store leftovers?
Store leftovers in an airtight container in the refrigerator for up to 3 days. Reheat gently on the stovetop or microwave, adding a splash of milk or cream to loosen the sauce.

Can I make this dish ahead of time?
You can prepare the chicken and sauce ahead of time and store them separately. Cook the pasta fresh and combine everything when ready to serve for the best texture.

If you loved this Southwest Chicken Alfredo, you might enjoy these other cheesy, comforting meals:

Conclusion:

Southwest Chicken Alfredo is the perfect blend of bold, zesty flavors and creamy indulgence. It’s a dish that’s simple to make yet packed with personality, making it a go-to for family dinners, date nights, or entertaining friends. Once you try it, you’ll understand why this recipe is bound to become a staple in your home. So grab your skillet, and let’s make dinner unforgettable tonight.

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Creamy Southwest Chicken Alfredo: A Bold Twist on Comfort Food


  • Author: Martha

Description

There’s nothing quite like a dish that feels indulgent yet manages to come together quickly, making it perfect for both busy weeknights and leisurely weekends. Southwest Chicken Alfredo is a shining example of comfort food that marries creamy richness with bold, zesty flavors. It’s a crowd-pleaser that warms the heart and satisfies the palate. This recipe is inspired by the bold flavors of the Southwest and the timeless appeal of Alfredo pasta, making it a true fusion masterpiece that’s hard to resist.

Picture this: tender, juicy strips of chicken, seasoned with a medley of chili powder, cumin, and smoky paprika, pan-seared to perfection for that golden, caramelized crust. Add to that a creamy Alfredo sauce with just the right kick of spice and tangy diced tomatoes for a burst of freshness. It’s all tossed with perfectly cooked penne pasta and topped with melted cheddar cheese, creating a velvety, cheesy finish that ties everything together. This dish not only delivers on flavor but also brings a sense of warmth and togetherness to the dinner table.

For many, this dish may evoke memories of family meals where lively conversation fills the room, and the tantalizing aroma of spices and cheese wafts from the kitchen. It’s the kind of meal that brings people back for seconds and leaves everyone asking for the recipe. Whether you’re looking for a new family favorite, a dish to impress guests, or just a comforting meal after a long day, Southwest Chicken Alfredo fits the bill perfectly.


Ingredients

Scale
  • Chicken Breasts: 1 pound, boneless and skinless, cut into 1-inch strips.
  • Penne Pasta: 8 ounces (about ½ pound).
  • Diced Tomatoes: One 15-ounce can, drained.
  • Heavy Cream: 1 cup.
  • Cheddar Cheese: 1½ cups, shredded.
  • Onion: 1 cup, chopped (yellow, white, or sweet).
  • Garlic Cloves: 4 cloves, minced.
  • Honey: 1 tablespoon.
  • Olive Oil: 1 tablespoon (or avocado or canola oil).
  • Butter: 1 tablespoon (salted or unsalted).
  • Cilantro: 2 tablespoons, chopped (for garnish).
  • Southwest Seasoning Blend:
    • 1½ teaspoons chili powder
    • ½ teaspoon cumin
    • ½ teaspoon oregano
    • 1 teaspoon paprika
    • ¼ teaspoon black pepper
    • ½ teaspoon salt
    • ⅛ teaspoon cayenne pepper

Instructions

Step 1: Prepare the Seasoning and Chicken

Begin by making the Southwest seasoning blend. Combine chili powder, cumin, oregano, paprika, black pepper, salt, and cayenne pepper in a small bowl. Stir until evenly mixed. Place the chicken strips in a large bowl, drizzle with honey, and sprinkle half of the seasoning mix over the chicken. Toss to coat the chicken thoroughly and let it sit while you prepare the other ingredients. This step ensures the chicken soaks up all those bold flavors.

Step 2: Cook the Pasta

Bring a large pot of salted water to a boil. Add the penne pasta and cook according to the package instructions until al dente. Drain the pasta and set it aside, reserving about ½ cup of pasta water in case you need it to thin the sauce later.

Step 3: Sear the Chicken

Heat olive oil in a large skillet over medium-high heat. Once the oil is shimmering, add the seasoned chicken strips in a single layer. Cook for 4-5 minutes per side until the chicken is golden brown and cooked through. The spices will create a beautiful crust on the chicken, locking in all the flavor. Remove the chicken from the skillet and set it aside on a plate.

Step 4: Sauté the Vegetables

In the same skillet, add the butter and chopped onions. Sauté over medium heat for 2-3 minutes until the onions become soft and translucent. Add the minced garlic and cook for an additional minute until fragrant. Then, stir in the diced tomatoes, letting the mixture simmer for 2-3 minutes to meld the flavors.

Step 5: Make the Creamy Sauce

Reduce the heat to low and pour in the heavy cream. Stir continuously, allowing the cream to warm through and absorb the flavors from the vegetables and spices left in the pan. Slowly add the shredded cheddar cheese, one handful at a time, stirring until the cheese melts completely into the sauce. If the sauce feels too thick, stir in a little of the reserved pasta water until you reach your desired consistency.

Step 6: Combine Everything

Add the cooked pasta to the skillet, tossing it in the creamy sauce to coat every piece evenly. Gently fold in the cooked chicken, ensuring it’s well distributed throughout the pasta. Let everything simmer together for 2-3 minutes so the flavors can meld.

Step 7: Garnish and Serve

Transfer the pasta to serving plates or a large serving bowl. Sprinkle chopped cilantro over the top for a fresh, vibrant touch. Serve immediately while the dish is warm and the cheese is gooey.

Notes

Feel free to customize the dish with additional vegetables like bell peppers, zucchini, or corn for extra texture and flavor.


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